"Fluid Challenge in Intensive Care: The FENICE Study - A Global Inception Cohort Study" is a research article that presents the findings of an observational study on the administration of fluid challenges in intensive care units (ICUs) around the world.
The FENICE (Fluid Expansion as Supportive Therapy) study gathered data from 2213 patients in 311 ICUs across 46 countries between 2013 and 2014. The aim was to better understand how fluid challenges are utilized in intensive care, and to determine if there are any common trends or patterns in their use.
Key findings of the study include:
1. Fluid challenges are commonly used in ICUs. Almost all patients (98%) received a fluid challenge during their stay in the ICU.
2. There are wide variations in the method of fluid challenge administration. The choice of fluid type, volume, duration, and criteria for response varied significantly between different ICUs.
3. Only a minority (16.6%) of fluid challenges were monitored using a non-invasive cardiac output monitoring tool, suggesting that response to fluid challenge may often be assessed subjectively rather than objectively.
4. Patients who received fluid challenges had a higher risk of developing pulmonary edema and acute kidney injury.
Despite the widespread use of fluid challenges, this study suggested there is insufficient standardized practice guidelines in this area, thus prompting the need for further research to establish best protocol and therapy management. |
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