Discovery of AZD4144, a Selective and Potent NLRP3 Inhibitor for the Treatment of Inflammatory Diseases

发表于 2026-7-3 08:43:27

期刊：Journal of Medicinal Chemistry

文献作者：Anders Johansson; Hiroshi Sugama; Niklas Larsson; Susanne Winiwarter; Kosuke Yoshida; Henrik Gradén; Giulia Bergonzini; Takehiko Matsumura; Shiki Miyazaki; Ryuichi Fuchigami; Masahiro Eda; Hisayuki Takamatsu; Kaori Iguchi; Mitsuya Hongu; Tetsuji Matsudaira; Daniel Hovdal; Marlene Fredenwall; Ulf Fahlander; Anna Luchniak; Johan Brengdahl; Bomi Jung; Magdalena Rhedin; Juhi Sardana; Akiko Idei; Yosuke Kato; Junpei Kimura; Jenny Viklund; Peter Brandt; Anna-Karin Sjogren; Yui Hibino; Kevin Woollard; Hikaru Yoneda

出版日期：2025-7-24

DOI号：10.1021/acs.jmedchem.5c00781

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c00781

文献链接：https://doi.org/10.1021/acs.jmedchem.5c00781

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Discovery of AZD4144, a Selective and Potent NLRP3 Inhibitor for the Treatment of Inflammatory Diseases

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