A Case Study on the Impact of Thermal Hydrolysis and Lactone Ring Opening of Linker-Payload on Drug-to-Antibody Ratio Determination in a Topoisomerase I Inhibitor-Based ADC

发表于 2026-7-14 13:30:07

期刊：Bioconjugate Chemistry

文献作者：Keying Liang; Xiaotong Zhou; Henghui Li; Yimei Lu; Fuming Zhang; Junmei Zeng; Xuanxuan Zhou; Yiqian Li; Hilaire Yam Fung Cheung; Kyu-Sung Lee; Yujie Zhang; April Xu; Jing Song

出版日期：2026-6-17

DOI号：10.1021/acs.bioconjchem.6c00140

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.6c00140

文献链接：https://doi.org/10.1021/acs.bioconjchem.6c00140

当前文献来源于 American Chemical Society (ACS)。

备注信息：

发表于 2026-7-14 13:30:08

: 当前求助已完成，请重新发起求助。
已完结状态的附件将会在24小时内删除。

[ACS] A Case Study on the Impact of Thermal Hydrolysis and Lactone Ring Opening of Linker-Payload on Drug-to-Antibody Ratio Determination in a Topoisomerase I Inhibitor-Based ADC

已采纳

同分类求助

最新回复

站点公告

今日热心研友

（热心研友QQ群）

[ACS] A Case Study on the Impact of Thermal Hydrolysis and Lactone Ring Opening of Linker-Payload on Drug-to-Antibody Ratio Determination in a Topoisomerase I Inhibitor-Based ADC 一键复制