Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration

发表于 2026-7-29 13:38:19

期刊：Bioorganic & Medicinal Chemistry Letters

文献作者：Simeon Bowers; Anh P. Truong; R. Jeffrey Neitz; Roy K. Hom; Jennifer M. Sealy; Gary D. Probst; David Quincy; Brian Peterson; Wayman Chan; Robert A. Galemmo; Andrei W. Konradi; Hing L. Sham; Gergely Tóth; Hu Pan; May Lin; Nanhua Yao; Dean R. Artis; Heather Zhang; Linda Chen; Mark Dryer; Bhushan Samant; Wes Zmolek; Karina Wong; Colin Lorentzen; Erich Goldbach; George Tonn; Kevin P. Quinn; John-Michael Sauer; Sarah Wright; Kyle Powell; Lany Ruslim; Zhao Ren; Frédérique Bard; Ted A. Yednock; Irene Griswold-Prenner

出版日期：2011-9-

DOI号：10.1016/j.bmcl.2011.06.100

下载链接：https://www.sciencedirect.com/sc ... 960894X11008912/pdf

文献链接：https://doi.org/10.1016/j.bmcl.2011.06.100

当前文献来源于 Elsevier BV。

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[Elsevier/Sciencedirect] Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration

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