Design and Synthesis of Pyrrolo[3,4-d]pyrimidine-Based ATR Degraders for Effective Treatment of Colorectal Cancer in Mouse Model

发表于 2026-7-30 12:05:33

期刊：Journal of Medicinal Chemistry

文献作者：Nian-Dong Mao; Zi Hui; Chen-Chen Wang; Meng-Lan He; Shun-Ran Li; Meng-Qian Yu; Lulu Ye; Jia-Wei Zhou; Zong-Hao Wang; Bo-Qun Du; Guo-Wei Ye; Yu-Qing Zhang; Xia Yao; Xing-Lin Feng; Frédéric Lirussi; Carmen Garrido; Yuan Gao; Hui Luo; Xiang-Yang Ye

出版日期：2026-3-26

DOI号：10.1021/acs.jmedchem.5c03155

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c03155

文献链接：https://doi.org/10.1021/acs.jmedchem.5c03155

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Design and Synthesis of Pyrrolo[3,4-d]pyrimidine-Based ATR Degraders for Effective Treatment of Colorectal Cancer in Mouse Model

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