Design of Novel Exatecan-Amide Linker-Payloads for the Development of Stable, Low-Aggregating, and Highly Efficacious Antibody-Drug Conjugates

发表于 2026-7-31 13:48:38

期刊：Journal of Medicinal Chemistry

文献作者：Ryan V. Quiroz; Simon B. Lang; Rebecca E. Johnson; Nancy Zepeda; Vlad Bacauanu; Christian L. Morales; Manoj Charati; John A. Flygare; Olivia R. Chastain; Zhong L. Hua; Edward P. Bowman; Bernhard H. Geierstanger; Alycia K. Uyeoka; Fan Zhang; Huimin Zhong; Esther Kofman; Daniela M. Tomazela; Laurence Fayadat-Dilman; Mengxuan Jia; Michael Judo; Ian Knemeyer; Peyman Akbari; Qingyun Yan; Evan R. Barry; Alan B. Northrup; W. Michael Seganish

出版日期：2026-5-14

DOI号：10.1021/acs.jmedchem.5c03706

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c03706

文献链接：https://doi.org/10.1021/acs.jmedchem.5c03706

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Design of Novel Exatecan-Amide Linker-Payloads for the Development of Stable, Low-Aggregating, and Highly Efficacious Antibody-Drug Conjugates

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