Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE)

发表于 2026-8-10 15:53:39

期刊：Journal of Medicinal Chemistry

文献作者：Pravin L Kotian; Minwan Wu; Satish Vadlakonda; Venkat Chintareddy; Pengcheng Lu; Luis Juarez; Debra Kellogg-Yelder; Xilin Chen; Saritha Muppa; Ramanda Chambers-Wilson; Cynthia Davis Parker; Jason Williams; Kevin J Polach; Weihe Zhang; Krishnan Raman; Yarlagadda S Babu

出版日期：2021-9-9

DOI号：10.1021/acs.jmedchem.1c00511

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00511

文献链接：https://doi.org/10.1021/acs.jmedchem.1c00511

当前文献来源于 American Chemical Society (ACS)。

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发表于 2026-8-10 15:53:40

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[ACS] Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE)

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[ACS] Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE) 一键复制