Design and Synthesis of a Novel Covalent Dihydropteridinone Derivative as a Highly Potent and Orally Bioavailable PLK1 Inhibitor for the Treatment of Chronic Myeloid Leukemia

发表于 4 天前

期刊：Journal of Medicinal Chemistry

文献作者：Jiaxu Zhou; Zhongtang Li; Xiaojiao Sun; Xiangyu Zhang; Yan He; Cheng Shi; Xiaowei Chi; Dehua Lu; Weiping Lyu; Siyu Xiu; Tingting Yang; Yanming Chen; Zhongwei Wang; Qi Li; Ruqiu Zheng; Jiarui Du; Yu Lin; Jinghao Yan; Tengfei Li; Chenzhong Liao; Liangren Zhang; Zhenming Liu

出版日期：--

DOI号：10.1021/acs.jmedchem.6c01512

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6c01512

文献链接：https://doi.org/10.1021/acs.jmedchem.6c01512

当前文献来源于 American Chemical Society (ACS)。

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发表于 4 天前

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[ACS] Design and Synthesis of a Novel Covalent Dihydropteridinone Derivative as a Highly Potent and Orally Bioavailable PLK1 Inhibitor for the Treatment of Chronic Myeloid Leukemia

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