Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis

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期刊：Journal of Medicinal Chemistry

文献作者：Robert A. Craig; Brian M. Fox; Cheng Hu; Katrina W. Lexa; Maksim Osipov; Arun P. Thottumkara; Martin Larhammar; Takashi Miyamoto; Anil Rana; Lesley A. Kane; Ernie Yulyaningsih; Hilda Solanoy; Hoang Nguyen; Roni Chau; Timothy Earr; Yuji Kajiwara; Daniel Fleck; Anthony Lucas; Patrick C. G. Haddick; Ryan H. Takahashi; Vincent Tong; Jing Wang; Mark J. Canet; Suresh B. Poda; Kimberly Scearce-Levie; Ankita Srivastava; Zachary K. Sweeney; Musheng Xu; Rui Zhang; Jianrong He; Yanan Lei; Zheng Zhuo; Javier de Vicente

出版日期：2022-12-22

DOI号：10.1021/acs.jmedchem.2c01056

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01056

文献链接：https://doi.org/10.1021/acs.jmedchem.2c01056

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis

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[ACS] Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis