Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase for B-Cell Malignancies and Autoimmune Diseases

发表于 2026-8-19 15:04:00

期刊：Journal of Medicinal Chemistry

文献作者：Yunhang Guo; Nan Hu; Ye Liu; Wei Zhang; Desheng Yu; Gongyin Shi; Bo Zhang; Longbo Yin; Min Wei; Xi Yuan; Lusong Luo; Fan Wang; Xiaomin Song; Lei Xin; Qiang Wei; Yong Li; Ying Guo; Shuaishuai Chen; Taichang Zhang; Shuo Zhang; Xing Zhou; Cuining Zhang; Dan Su; Junhua Liu; Zhenzhen Cheng; Jiye Zhang; Haimei Xing; Hanzi Sun; Xin Li; Yuan Zhao; Min He; Yue Wu; Yin Guo; Xuebing Sun; Alice Tian; Changyou Zhou; Steve Young; Xuesong Liu; Lai Wang; Zhiwei Wang

出版日期：2023-3-23

DOI号：10.1021/acs.jmedchem.2c01938

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01938

文献链接：https://doi.org/10.1021/acs.jmedchem.2c01938

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase for B-Cell Malignancies and Autoimmune Diseases

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