Design, Synthesis, and Unprecedented Interactions of Covalent Dipeptide-Based Inhibitors of SARS-CoV-2 Main Protease and Its Variants Displaying Potent Antiviral Activity

发表于 2026-8-21 11:22:41

期刊：Journal of Medicinal Chemistry

文献作者：Philipp Flury; Nadine Krüger; Katharina Sylvester; Julian Breidenbach; Ghazl Al Hamwi; Jingxin Qiao; Yan Chen; Cheila Rocha; Mateus Sá Magalhaes Serafim; Elany Barbosa da Silva; Stefan Pohlmann; Antti Poso; Thales Kronenberger; Katharina Rox; Anthony J. O’Donoghue; Shengyong Yang; Norbert Strater; Michael Gütschow; Stefan A. Laufer; Christa E. Müller; Thanigaimalai Pillaiyar

出版日期：2025-2-13

DOI号：10.1021/acs.jmedchem.4c02254

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c02254

文献链接：https://doi.org/10.1021/acs.jmedchem.4c02254

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Design, Synthesis, and Unprecedented Interactions of Covalent Dipeptide-Based Inhibitors of SARS-CoV-2 Main Protease and Its Variants Displaying Potent Antiviral Activity

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