Discovery of a Series of Substituted 1H-((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators

发表于 2026-8-21 15:42:44

期刊：Journal of Medicinal Chemistry

文献作者：Christine F. Gelin; Brice Stenne; Heather Coate; Afton Hiscox; Akinola Soyode-Johnson; Jessica L. Wall; Brian Lord; Jeffrey Schoellerman; Kevin J. Coe; Kai Wang; Jesus Alcázar; Christa C. Chrovian; Curt A. Dvorak; Nicholas I. Carruthers; Tatiana Koudriakova; Bartosz Balana; Michael A. Letavic

出版日期：2023-2-23

DOI号：10.1021/acs.jmedchem.2c01916

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01916

文献链接：https://doi.org/10.1021/acs.jmedchem.2c01916

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Discovery of a Series of Substituted 1H-((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators

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[ACS] Discovery of a Series of Substituted 1H-((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators 一键复制