Discovery and Characterization of a First-In-Class HCK/BTK PROTAC DFCI-002-06 for the Treatment of MYD88 Mutated B Cell Malignancies

发表于 2026-9-3 11:11:14

期刊：Journal of Medicinal Chemistry

文献作者：John M. Hatcher; Shirong Liu; Amanda Kofides; Alexa Canning; Dominic Pizzarella; Xia Liu; Nickolas Tsakmaklis; Maria Guerrera; Christopher Patterson; Alberto Guijosa; Prafulla Gokhale; Zachary Hunter; Shayna Sarosiek; Jorge Castillo; Jinhua Wang; Sara J. Buhrlage; Steven P. Treon

出版日期：2026-1-22

DOI号：10.1021/acs.jmedchem.5c02444

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c02444

文献链接：https://doi.org/10.1021/acs.jmedchem.5c02444

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Discovery and Characterization of a First-In-Class HCK/BTK PROTAC DFCI-002-06 for the Treatment of MYD88 Mutated B Cell Malignancies

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