Discovery of a Novel Dihydroisoquinolinone Derivative as a Potent CDK9 Inhibitor Capable of Overcoming L156F Mutant for the Treatment of Hematologic Malignancies

发表于 2026-9-13 16:46:26

期刊：Journal of Medicinal Chemistry

文献作者：Chenliang Shi; Yun Wu; Fengming Zou; Yuan Yuan; Chen Hu; Qingwang Liu; Chao Wu; Lijuan Shen; Aoli Wang; Wenchao Wang; Beilei Wang; Jing Liu; Qingsong Liu

出版日期：2025-4-24

DOI号：10.1021/acs.jmedchem.4c02548

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c02548

文献链接：https://doi.org/10.1021/acs.jmedchem.4c02548

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Discovery of a Novel Dihydroisoquinolinone Derivative as a Potent CDK9 Inhibitor Capable of Overcoming L156F Mutant for the Treatment of Hematologic Malignancies

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