Discovery and Evaluation of E0714 as an Antiepileptic Candidate: A Highly Subtype-Selective Kv7 Agonist within the Kv7 Family Designed Based on a Kv7.2-Specific Pocket

发表于 2026-9-16 15:38:22

期刊：Journal of Medicinal Chemistry

文献作者：Kening Qiao; Weidong Zhao; Yawen Cao; Tingting Li; Lingfang Wei; Xingang Liu; Yan Liu; Jincan Li; Chunxiao Chen; Fan Zhang; Yang Zhang; Xuedong Li; Qingzhong Jia

出版日期：2026-3-12

DOI号：10.1021/acs.jmedchem.5c03052

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c03052

文献链接：https://doi.org/10.1021/acs.jmedchem.5c03052

当前文献来源于 American Chemical Society (ACS)。

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发表于 2026-9-16 15:38:23

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[ACS] Discovery and Evaluation of E0714 as an Antiepileptic Candidate: A Highly Subtype-Selective Kv7 Agonist within the Kv7 Family Designed Based on a Kv7.2-Specific Pocket

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