Discovery of Tetrasubstituted Quinazolin-4(3H)-ones as Wild-type-sparing, Highly Selective PI3KαH1047R Inhibitors

发表于 2026-9-22 12:17:34

期刊：Journal of Medicinal Chemistry

文献作者：Chun Chen; Ryan Holmes; Jack Carter; Soham Maity; Sarah B. Pawley; Nicholaas Stahl; Amy Crossan; Joseph D. Rager; Ashish Juvekar; Min Wang; Chaoyi Xu; Ross Kuskovsky; Monisha Sivakumar; Kirsten Gallagher; Raul Leal; Sandy Geeganage; Peggy Scherle; Andrew P. Combs; Andrew W. Buesking

出版日期：--

DOI号：10.1021/acs.jmedchem.6c00269

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6c00269

文献链接：https://doi.org/10.1021/acs.jmedchem.6c00269

当前文献来源于 American Chemical Society (ACS)。

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发表于 2026-9-22 12:17:35

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[ACS] Discovery of Tetrasubstituted Quinazolin-4(3H)-ones as Wild-type-sparing, Highly Selective PI3KαH1047R Inhibitors

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[ACS] Discovery of Tetrasubstituted Quinazolin-4(3H)-ones as Wild-type-sparing, Highly Selective PI3KαH1047R Inhibitors 一键复制