Design, Synthesis, and Evaluation of Nucleolin-Bridged, MDM2-Recruiting IRAK4 Degraders for the Treatment of Autoimmune Diseases

发表于 2026-9-22 14:27:45

期刊：Journal of Medicinal Chemistry

文献作者：Ziting Feng; Xiaoxuan Zhang; Yi Ding; Kang Zhang; Fang Qiu; Duoli Xie; Aiping Lu; Lingqiang Zhang; Chao Liang

出版日期：2026-2-26

DOI号：10.1021/acs.jmedchem.5c03507

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c03507

文献链接：https://doi.org/10.1021/acs.jmedchem.5c03507

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Design, Synthesis, and Evaluation of Nucleolin-Bridged, MDM2-Recruiting IRAK4 Degraders for the Treatment of Autoimmune Diseases

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