The study "Global Stage Distribution of Breast Cancer at Diagnosis: A Systematic Review and Meta-Analysis," published in JAMA Oncology, provides an extensive analysis of the stage distribution of breast cancer at diagnosis on a global scale. This research is significant because the stage of cancer at diagnosis is a crucial factor for predicting survival outcomes.发表在《美国医学会肿瘤学杂志》（JAMA Oncology）上的研究“诊断时乳腺癌的全球分期分布：系统评价和荟萃分析”对全球范围内乳腺癌诊断时的分期分布进行了广泛的分析。这项研究意义重大，因为诊断时癌症的分期是预测生存结果的关键因素。
Key findings of the study include:该研究的主要发现包括：
The research assessed the global distribution of breast cancer stages by examining factors like country, age group, calendar period, and socioeconomic status using population-based data.该研究通过使用基于人口的数据检查国家、年龄组、日历时期和社会经济地位等因素来评估乳腺癌分期的全球分布。
The data encompassed over 2.4 million women with breast cancer from 81 countries.该数据包括来自81个国家的240多万名乳腺癌女性。
There were notable disparities in the stage of breast cancer at diagnosis. For instance, the proportion of cases with distant metastatic breast cancer at diagnosis was high in sub-Saharan Africa, ranging from 5.6% to 30.6%, and low in North America, ranging from 0.0% to 6.0%.诊断时乳腺癌分期存在显著差异。例如，在撒哈拉以南非洲地区，诊断时患有远处转移性乳腺癌的病例比例很高，从5.6%到30.6%不等，在北美很低，从0.0%到6.0%不等。
The study observed a decline in the proportion of patients diagnosed with distant metastatic disease over the past two decades. However, there were instances of stabilization or slight increases in some regions.该研究观察到，在过去二十年中，被诊断为远处转移性疾病的患者比例有所下降。然而，在一些地区出现了稳定或略有增加的情况。
The research highlighted the relationship between older age, lower socioeconomic status, and higher proportions of cases diagnosed at a distant metastatic stage.该研究强调了高龄、较低的社会经济地位和在远处转移阶段诊断出的病例比例较高之间的关系。
The study concludes that effective policies and interventions have led to a decrease in the proportions of women diagnosed with metastatic breast cancer at diagnosis in high-income countries. However, persistent inequalities need to be addressed through increased awareness and early detection initiatives. The study emphasizes the importance of improving global coverage and quality of population-based cancer registries, particularly in the collection of standardized stage data, to monitor progress effectively.该研究得出的结论是，有效的政策和干预措施导致高收入国家在诊断时被诊断为转移性乳腺癌的妇女比例下降。然而，需要通过提高认识和早期发现举措来解决持续存在的不平等问题。该研究强调了提高基于人群的癌症登记处的全球覆盖率和质量的重要性，特别是在收集标准化阶段数据方面，以有效监测进展情况。 |
求助已关闭
30