Major Progress in the Liquid-Phase Synthesis ofN-Alkyl-Rich Cyclic Peptides: Kilogram-Scale GMP Production of the KRAS Inhibitor LUNA18

发表于 2026-7-15 16:17:16

期刊：Organic Process Research & Development

文献作者：Zengye Hou; Shio Komiya; Kotaro Iwasaki; Yasuhiro Kondo; Yousuke Momose; Kiyoshi Sasakura; Kota Tanaka; Manabu Wadamoto; Peithing Chia; Katsunori Dan; Hirotaka Ejima; Hiroki Fujisawa; Akira Fukuzawa; Shohei Hashimoto; Takenori Ishizawa; Hisashi Ito; Yuki Nakagawa; Hitomi Sato; Nao Sato; Hiroko Sekita; Hiroki Serizawa; Sayako Tamura; Taro Enomoto; Akie Honma; Takuma Ikeda; Masatoshi Murakata; Junichi Shiina; Takahiko Yabuzaki; Masao Tsukazaki; Hiroshi Iwamura; Kenji Maeda

出版日期：2025-11-21

DOI号：10.1021/acs.oprd.5c00260

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.5c00260

文献链接：https://doi.org/10.1021/acs.oprd.5c00260

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Major Progress in the Liquid-Phase Synthesis ofN-Alkyl-Rich Cyclic Peptides: Kilogram-Scale GMP Production of the KRAS Inhibitor LUNA18

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