Discovery of BMS-986458, a Potent and Selective B-Cell Lymphoma 6 Protein Ligand-Directed Degrader, for the Treatment of B-Cell Non-Hodgkin Lymphoma

发表于 2026-7-30 11:23:17

期刊：Journal of Medicinal Chemistry

文献作者：Deborah S. Mortensen; Hunter P. Shunatona; Natalie Holmberg-Douglas; Jayce Rhodes; Diogo Da Silva; Jim Gamez; Matt Groza; Jinyi Zhu; Andy Christoforou; Scott A. Johnson; Godrej Khambatta; Rama Krishna Narla; Roshan Y Nimje; Dehua Huang; Dharmpal S. Dodd; Jennifer Griffin; Giulianna Miseo; Brandon Whitefield; Dahlia R. Weiss; James Rader; Elif Kuzu; Jim Leisten; Chon Lai; Lihong Shi; Joselyn Del Rosario; Deepak Dalvie; Mark Rolfe; Christoph W. Zapf; Peter Belmont; Matt Alexander; Neil Bence; Lynda Groocock

出版日期：2026-2-26

DOI号：10.1021/acs.jmedchem.5c03123

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c03123

文献链接：https://doi.org/10.1021/acs.jmedchem.5c03123

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Discovery of BMS-986458, a Potent and Selective B-Cell Lymphoma 6 Protein Ligand-Directed Degrader, for the Treatment of B-Cell Non-Hodgkin Lymphoma

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