Discovery and Optimization of Orally Bioavailable Heterobifunctional Degraders of KAT2A/B for the Treatment of Cancer

发表于 2026-7-30 11:23:43

期刊：Journal of Medicinal Chemistry

文献作者：James Neef; Kimberly S. Straley; Chinmoy Mukherjee; Amol Tipnis; Suleman Riyajsaheb Maujan; Maulasri Bhatta; Sambad Sharma; Sara Sinicropi-Yao; Joe DeBartolo; Andrew J. McRiner; Betty Chan; Henry Wilson; Christina S. Lee; Zied Boudhraa; Mohamed El Ezzy; Mark Bittinger; Laura Jennings Antipov; Thomas G. Graeber; Katharine E. Yen; David S. Millan

出版日期：2026-2-26

DOI号：10.1021/acs.jmedchem.5c03208

下载链接：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c03208

文献链接：https://doi.org/10.1021/acs.jmedchem.5c03208

当前文献来源于 American Chemical Society (ACS)。

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[ACS] Discovery and Optimization of Orally Bioavailable Heterobifunctional Degraders of KAT2A/B for the Treatment of Cancer

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